A novel screening method for dihydrofolate reductase inhibitors (DHFRI) using high performance capillary electrophoresis (HPCE) was developed.
建立了一种采用毛细管电泳法(CE)测定二氢叶酸还原酶(DHFR)反应动力学参数的新方法。
This method has been applied to the design of inhibitors for E. coli dihydrofolate reductase and human phospholipase A2.
该方法已用于设计抑制剂大肠杆菌二氢叶酸还原酶和人类磷脂酶a2。
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